multicrispr: gRNA design for prime editing and parallel targeting of thousands of targets

Targeting the coding genome to introduce nucleotide deletions/insertions via the CRISPR/Cas9 technology has become a standard procedure. It has quickly spawned a multitude of methods such as prime editing, APEX proximity labeling, or homology directed repair, for which supporting bioinformatics tool...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Life Sci Alliance
Main Authors: Bhagwat, Aditya M, Graumann, Johannes, Wiegandt, Rene, Bentsen, Mette, Welker, Jordan, Kuenne, Carsten, Preussner, Jens, Braun, Thomas, Looso, Mario
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494814/
https://ncbi.nlm.nih.gov/pubmed/32907859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000757
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