EGFR/Ras-induced CCL20 production modulates the tumour microenvironment

BACKGROUND: The activation of the EGFR/Ras-signalling pathway in tumour cells induces a distinct chemokine repertoire, which in turn modulates the tumour microenvironment. METHODS: The effects of EGFR/Ras on the expression and translation of CCL20 were analysed in a large set of epithelial cancer ce...

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Udgivet i:Br J Cancer
Main Authors: Hippe, Andreas, Braun, Stephan Alexander, Oláh, Péter, Gerber, Peter Arne, Schorr, Anne, Seeliger, Stephan, Holtz, Stephanie, Jannasch, Katharina, Pivarcsi, Andor, Buhren, Bettina, Schrumpf, Holger, Kislat, Andreas, Bünemann, Erich, Steinhoff, Martin, Fischer, Jens, Lira, Sérgio A., Boukamp, Petra, Hevezi, Peter, Stoecklein, Nikolas Hendrik, Hoffmann, Thomas, Alves, Frauke, Sleeman, Jonathan, Bauer, Thomas, Klufa, Jörg, Amberg, Nicole, Sibilia, Maria, Zlotnik, Albert, Müller-Homey, Anja, Homey, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493992/
https://ncbi.nlm.nih.gov/pubmed/32601464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0943-2
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