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Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton

Small molecule inhibitors are prime reagents for studies in microtubule cytoskeleton research, being applicable across a range of biological models and not requiring genetic engineering. However, traditional chemical inhibitors cannot be experimentally applied with spatiotemporal precision suiting t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Müller-Deku, Adrian, Meiring, Joyce C. M., Loy, Kristina, Kraus, Yvonne, Heise, Constanze, Bingham, Rebekkah, Jansen, Klara I., Qu, Xiaoyi, Bartolini, Francesca, Kapitein, Lukas C., Akhmanova, Anna, Ahlfeld, Julia, Trauner, Dirk, Thorn-Seshold, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493900/
https://ncbi.nlm.nih.gov/pubmed/32934232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18389-6
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