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Variable-order reference-free variant discovery with the Burrows-Wheeler Transform

BACKGROUND: In [Prezza et al., AMB 2019], a new reference-free and alignment-free framework for the detection of SNPs was suggested and tested. The framework, based on the Burrows-Wheeler Transform (BWT), significantly improves sensitivity and precision of previous de Bruijn graphs based tools by ov...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Prezza, Nicola, Pisanti, Nadia, Sciortino, Marinella, Rosone, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493873/
https://ncbi.nlm.nih.gov/pubmed/32938358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03586-3
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