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Scale-Up of the Manufacturing Process To Produce Docetaxel-Loaded mPEG-b-p(HPMA-Bz) Block Copolymer Micelles for Pharmaceutical Applications
[Image: see text] An efficient, scalable, and good manufacturing practice (GMP) compatible process was developed for the production of docetaxel-loaded poly(ethylene glycol)-b-poly(N-2-benzoyloxypropyl methacrylamide) (mPEG-b-p(HPMA-Bz)) micelles. First, the synthesis of the mPEG-b-p(HPMA-Bz) block...
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| Опубликовано в: : | Org Process Res Dev |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American
Chemical Society
2019
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7493301/ https://ncbi.nlm.nih.gov/pubmed/32952390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.oprd.9b00387 |
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