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Automated Solution-Phase Synthesis of S-Glycosides for the Production of Oligomannopyranoside Derivatives

Thioglycosides are more resistant to enzymatic hydrolysis than their O-linked counterparts, thereby becoming attractive targets for carbohydrate-based therapeutic development. We report the first development of methods for the site-selective incorporation of S-linkages into automated solution-phase...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Kern, Mallory K., Pohl, Nicola L. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493207/
https://ncbi.nlm.nih.gov/pubmed/32432478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01236
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