BRCA Mutations in Prostate Cancer: Prognostic and Predictive Implications

Despite chemotherapy and novel androgen-receptor signalling inhibitors (ARSi) have been approved during the last decades, metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease with poor clinical outcomes. Several studies found that germline or acquired DNA damage repair (D...

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Vydáno v:J Oncol
Hlavní autoři: Messina, Carlo, Cattrini, Carlo, Soldato, Davide, Vallome, Giacomo, Caffo, Orazio, Castro, Elena, Olmos, David, Boccardo, Francesco, Zanardi, Elisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492871/
https://ncbi.nlm.nih.gov/pubmed/32963528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4986365
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