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Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study

BACKGROUND: The virological and immunological effects of the immunomodulatory drugs used for COVID-19 remain unknown. We evaluated the impact of interleukin (IL)-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and the antibody response in patients with COVID-19. METHODS: Prospective cohort...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Masiá, Mar, Fernández-González, Marta, Padilla, Sergio, Ortega, Piedad, García, José A., Agulló, Vanesa, García-Abellán, Javier, Telenti, Guillermo, Guillén, Lucía, Gutiérrez, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492814/
https://ncbi.nlm.nih.gov/pubmed/32950003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102999
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