Chloroquine Treatment Suppresses Mucosal Inflammation in a Mouse Model of Eosinophilic Chronic Rhinosinusitis

PURPOSE: The Toll-like receptor 9 (TLR9) signaling pathway is involved in the pathogenesis of chronic rhinosinusitis (CRS) with nasal polyposis. The aim of this study was to assess the therapeutic potential of the TLR9 pathway inhibitor chloroquine in CRS mice. METHODS: The expression of type I inte...

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Vydáno v:Allergy Asthma Immunol Res
Hlavní autoři: Choi, Mi-Ra, Xu, Jun, Lee, Seulgi, Yeon, Sun-Hee, Park, Soo-Kyoung, Rha, Ki-Sang, Kim, Yong Min
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492509/
https://ncbi.nlm.nih.gov/pubmed/32935491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2020.12.6.994
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