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Understanding Selenium and Glutathione as Antiviral Factors in COVID-19: Does the Viral M(pro) Protease Target Host Selenoproteins and Glutathione Synthesis?

Glutathione peroxidases (GPX), a family of antioxidant selenoenzymes, functionally link selenium and glutathione, which both show correlations with clinical outcomes in COVID-19. Thus, it is highly significant that cytosolic GPX1 has been shown to interact with an inactive C145A mutant of M(pro), th...

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Detalhes bibliográficos
Publicado no:Front Nutr
Main Authors: Taylor, Ethan Will, Radding, Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492384/
https://ncbi.nlm.nih.gov/pubmed/32984400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnut.2020.00143
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