Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy

The ubiquitin–proteasome system has the capacity to degrade polyubiquitinated proteins and plays an important role in many cellular processes. However, the role of Rpt3, a crucial proteasomal gene, has not been investigated in adult muscles in vivo. Herein, we generated skeletal-muscle-specific Rpt3...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Kitajima, Yasuo, Suzuki, Naoki, Yoshioka, Kiyoshi, Izumi, Rumiko, Tateyama, Maki, Tashiro, Yoshitaka, Takahashi, Ryosuke, Aoki, Masashi, Ono, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492297/
https://ncbi.nlm.nih.gov/pubmed/32984340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00859
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