Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor

BACKGROUND: The protein syntenin-1 is expressed by a variety of cell types, and is upregulated in various malignancies, including melanoma, breast cancer and glioma. Although the mechanism by which elevated syntenin-1 expression contributes to cancer has been described, the exact pathway has not bee...

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Pubblicato in:Br J Cancer
Autori principali: Iwamoto, Kazuya, Takahashi, Hidekazu, Okuzaki, Daisuke, Osawa, Hideo, Ogino, Takayuki, Miyoshi, Norikatsu, Uemura, Mamoru, Matsuda, Chu, Yamamoto, Hirofumi, Mizushima, Tsunekazu, Mori, Masaki, Doki, Yuichiro, Eguchi, Hidetoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492211/
https://ncbi.nlm.nih.gov/pubmed/32595209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0965-9
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