Intranasal IL-4 Administration Alleviates Functional Deficits of Periventricular Leukomalacia in Neonatal Mice

Background: Periventricular leukomalacia (PVL) is the major form of brain injury in premature infants. Currently, there are no therapies to treat PVL. Several studies suggested that polarization of microglia, a resident macrophage-like immune cell in the central nervous system, plays a vital role in...

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Bibliographic Details
Published in:Front Neurol
Main Authors: Yu, Lin-chao, Miao, Jing-kun, Li, Wei-bin, Chen, Na, Chen, Qi-xiong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neurology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492203/
https://ncbi.nlm.nih.gov/pubmed/32982939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.00930
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