Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells

HIV transmission via genital and colorectal mucosa are the most common routes of dissemination. Here, we explored the effects of free and complement-opsonized HIV on colorectal tissue. Initially, there was higher antiviral responses in the free HIV compared to complement-opsonized virus. The mucosal...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bhattacharya, Pradyot, Ellegård, Rada, Khalid, Mohammad, Svanberg, Cecilia, Govender, Melissa, Keita, Åsa V, Söderholm, Johan D, Myrelid, Pär, Shankar, Esaki M, Nyström, Sofia, Larsson, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492089/
https://ncbi.nlm.nih.gov/pubmed/32876566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57869
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