Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity

Angiotensin-converting enzyme 2 (ACE2) maintains cardiovascular and renal homeostasis but also serves as the entry receptor for the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), the causal agent of novel coronavirus disease 2019 (COVID-19)(1). COVID-19 disease severity, while hig...

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Vydáno v:bioRxiv
Hlavní autoři: Inde, Zintis, Yapp, Clarence, Joshi, Gaurav N., Spetz, Johan, Fraser, Cameron, Deskin, Brian, Ghelfi, Elisa, Sodhi, Chhinder, Hackam, David J., Kobzik, Lester, Croker, Ben A., Brownfield, Douglas, Jia, Hongpeng, Sarosiek, Kristopher A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491524/
https://ncbi.nlm.nih.gov/pubmed/32935109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.13.276923
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