Mast Cell Infiltration Is Associated With Persistent Symptoms and Endoscopic Abnormalities Despite Resolution of Eosinophilia in Pediatric Eosinophilic Esophagitis

OBJECTIVES: Mast cells (MCs) are increased in eosinophilic esophagitis (EoE). Endoscopic abnormalities, symptoms, and epithelial changes can persist after treatment despite a reduction of esophageal eosinophilia. It is unknown whether this could be due to persistent MC infiltration. We aimed to dete...

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Pubblicato in:Am J Gastroenterol
Autori principali: Bolton, Scott M., Kagalwalla, Amir F., Arva, Nicoleta C., Wang, Ming-Yu, Amsden, Katie, Melin-Aldana, Hector, Dellon, Evan S., Bryce, Paul J., Wershil, Barry K., Wechsler, Joshua B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491279/
https://ncbi.nlm.nih.gov/pubmed/31913192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ajg.0000000000000474
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