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Successful treatment of metastatic refractory gestational choriocarcinoma with pembrolizumab: A case for immune checkpoint salvage therapy in trophoblastic tumors
• Cure rates are high for choriocarcinoma, however chemoresistant disease often leads to death. • High expression of PD-L1 suggests a role for checkpoint inhibitors in choriocarcinoma. • Pembrolizumab should be considered for salvage therapy for chemoresistant choriocarcinoma.
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Pubblicato in: | Gynecol Oncol Rep |
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Autori principali: | , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Elsevier
2020
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7490982/ https://ncbi.nlm.nih.gov/pubmed/32964090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2020.100625 |
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