CDK4/6 inhibitors: a novel strategy for tumor radiosensitization

Recently, the focus of enhancing tumor radiosensitivity has shifted from chemotherapeutics to targeted therapies. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are a novel class of selective cell cycle therapeutics that target the cyclin D-CDK4/6 complex and induce G1 phase arrest. These agent...

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Bibliografische gegevens
Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Yang, Yilan, Luo, Jurui, Chen, Xingxing, Yang, Zhaozhi, Mei, Xin, Ma, Jinli, Zhang, Zhen, Guo, Xiaomao, Yu, Xiaoli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490904/
https://ncbi.nlm.nih.gov/pubmed/32933570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01693-w
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