Lymph node stromal CCL2 limits antibody responses

Nonhematopoietic stromal cells in lymph nodes such as fibroblastic reticular cells (FRCs) can support the survival of plasmablasts and plasma cells (together, antibody-forming cells (AFCs)). However, a regulatory function for the stromal compartment in AFC accumulation has not been appreciated. Here...

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Publicat a:Sci Immunol
Autors principals: Dasoveanu, Dragos C., Park, Hyeung Ju, Ly, Catherine L., Shipman, William D., Chyou, Susan, Kumar, Varsha, Tarlinton, David, Ludewig, Burkhard, Mehrara, Babak J., Lu, Theresa T.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490901/
https://ncbi.nlm.nih.gov/pubmed/32198221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw0693
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