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The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network

Atlastin (ATL) is a class of dynamin-like GTPases shaping endoplasmic reticulum (ER) by mediating homotypic membrane fusion. Defect of ATLs leads to abnormal ER structure and hereditary spastic paraplegia (HSP), a neurodegenerative disease with progressive spasticity. How ATLs are regulated to maint...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Zhao, Yupeng, Feng, Zhigang, Zou, Yan, Liu, Yanfen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490852/
https://ncbi.nlm.nih.gov/pubmed/32916628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101494
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