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In Vitro and In Vivo Amenability to Migalastat in Fabry Disease

Migalastat (1-deoxygalactonojirimycin) is approved for the treatment of Fabry disease (FD) in patients with an amenable mutation. Currently, there are at least 367 amenable and 711 non-amenable mutations known, based on an in vitro good laboratory practice (GLP) assay. Recent studies demonstrated th...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Lenders, Malte, Stappers, Franciska, Brand, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490640/
https://ncbi.nlm.nih.gov/pubmed/32995357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.08.012
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