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Carnitine metabolism in the human gut: characterization of the two-component carnitine monooxygenase CntAB from Acinetobacter baumannii

Bacterial formation of trimethylamine (TMA) from carnitine in the gut microbiome has been linked to cardiovascular disease. During this process, the two-component carnitine monooxygenase (CntAB) catalyzes the oxygen-dependent cleavage of carnitine to TMA and malic semialdehyde. Individual redox stat...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Massmig, Marco, Reijerse, Edward, Krausze, Joern, Laurich, Christoph, Lubitz, Wolfgang, Jahn, Dieter, Moser, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489909/
https://ncbi.nlm.nih.gov/pubmed/32694223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014266
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