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PIK3CA Mutational Status is Associated with High Glycolytic Activity in ER+/HER2- Early Invasive Breast Cancer: a Molecular Imaging study using [(18)F]FDG PET/CT

PURPOSE: In PIK3CA mutant breast cancer, downstream hyperactivation of the PI3K/AKT/mTOR pathway may be associated with increased glycolysis of cancer cells. The purpose of this study was to investigate the functional association of PIK3CA mutational status and tumor glycolysis in invasive ER+/HER2−...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Magometschnigg, Heinrich, Pinker, Katja, Helbich, Thomas, Brandstetter, Anita, Rudas, Margaretha, Nakuz, Thomas, Baltzer, Pascal, Wadsak, Wolfgang, Hacker, Marcus, Weber, Michael, Dubsky, Peter, Filipits, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489296/
https://ncbi.nlm.nih.gov/pubmed/30652258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-01308-z
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