Intra-Articular Delivery of Quercetin Using Thermosensitive Hydrogel Attenuate Cartilage Degradation in an Osteoarthritis Rat Model

OBJECTIVE: Quercetin (Que), a bioflavonoid, is both anti-inflammatory and antioxidative. Que has been used as an oral supplement for osteoarthritis (OA) with inconsistent findings because of its low bioavailability. We encapsulated Que in a mPEG-polypeptide thermogel to prolong its bioactivity. The...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cartilage
Asıl Yazarlar: Mok, Sze-Wing, Fu, Sai-Chuen, Cheuk, Yau-Chuk, Chu, I-Ming, Chan, Kai-Ming, Qin, Ling, Yung, Shu-Hang, Kevin Ho, Ki-Wai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2018
Konular:
Basic Science
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488941/
https://ncbi.nlm.nih.gov/pubmed/30160166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603518796550
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