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Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies

Recent long-read assemblies often exceed the quality and completeness of available reference genomes, making validation challenging. Here we present Merqury, a novel tool for reference-free assembly evaluation based on efficient k-mer set operations. By comparing k-mers in a de novo assembly to thos...

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Foilsithe in:Genome Biol
Main Authors: Rhie, Arang, Walenz, Brian P., Koren, Sergey, Phillippy, Adam M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488777/
https://ncbi.nlm.nih.gov/pubmed/32928274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02134-9
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