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High-dose N-acetylcysteine for long-term, regular treatment of early-stage chronic obstructive pulmonary disease (GOLD I–II): study protocol for a multicenter, double-blinded, parallel-group, randomized controlled trial in China

INTRODUCTION: The presence of increased oxidative stress and airway inflammation has been proven in subjects with chronic obstructive pulmonary disease (COPD). Several studies have demonstrated that drugs with antioxidant and anti-inflammatory properties such as N-acetylcysteine (NAC) can reduce the...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Tian, Heshen, Zhou, Yumin, Tang, Longhui, Wu, Fan, Deng, Zhishan, Lin, Bijia, Huang, Peiyu, Wei, Shaodan, Zhao, Dongxing, Zheng, Jingping, Zhong, Nanshan, Ran, Pixin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488567/
https://ncbi.nlm.nih.gov/pubmed/32917271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04701-8
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