T2 heterogeneity: a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment

BACKGROUND: Early Alzheimer’s disease (AD) diagnosis is vital for development of disease-modifying therapies. Prior to significant brain tissue atrophy, several microstructural changes take place as a result of Alzheimer’s pathology. These include deposition of amyloid, tau and iron, as well as alte...

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Bibliografiske detaljer
Udgivet i:Alzheimers Res Ther
Main Authors: Wearn, Alfie R., Nurdal, Volkan, Saunders-Jennings, Esther, Knight, Michael J., Isotalus, Hanna K., Dillon, Serena, Tsivos, Demitra, Kauppinen, Risto A., Coulthard, Elizabeth J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488446/
https://ncbi.nlm.nih.gov/pubmed/32912337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00672-9
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