MicroRNA-27b targets CBFB to inhibit differentiation of human bone marrow mesenchymal stem cells into hypertrophic chondrocytes

BACKGROUND: Human bone marrow-derived mesenchymal stem cells (hBMSCs) have chondrocyte differentiation potential and are considered to be a cell source for cell-transplantation-mediated repair of cartilage defects, including those associated with osteoarthritis (OA). However, chondrocyte hypertrophi...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Lv, Shuang, Xu, Jinying, Chen, Lin, Wu, Haitao, Feng, Wei, Zheng, Yangyang, Li, Pengdong, Zhang, Haiying, Zhang, Lihong, Chi, Guangfan, Li, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488425/
https://ncbi.nlm.nih.gov/pubmed/32917285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01909-y
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