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Disruption in iron homeostasis and impaired activity of iron-sulfur cluster containing proteins in the yeast model of Shwachman-Diamond syndrome

BACKGROUND: Shwachman-Diamond syndrome (SDS) is a congenital disease that affects the bone marrow, skeletal system, and pancreas. The majority of patients with SDS have mutations in the SBDS gene, involved in ribosome biogenesis as well as other processes. A Saccharomyces cerevisiae model of SDS, la...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Jain, Ayushi, Nilatawong, Phubed, Mamak, Narinrat, Jensen, Laran T., Jensen, Amornrat Naranuntarat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488397/
https://ncbi.nlm.nih.gov/pubmed/32944219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00468-2
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