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Chemically defined human vascular laminins for biologically relevant culture of hiPSC-derived brain microvascular endothelial cells

BACKGROUND: In recent years, differentiation of human induced pluripotent stem cells (hiPSCs) into brain-specific microvascular endothelial cells (iBMECs) has frequently been used to model the blood–brain barrier (BBB). However, there are limitations in the use of iBMECs for in vitro studies, such a...

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Bibliografiske detaljer
Udgivet i:Fluids Barriers CNS
Main Authors: Motallebnejad, Pedram, Azarin, Samira M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488267/
https://ncbi.nlm.nih.gov/pubmed/32912242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-00215-2
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