The combination of an inflammatory peripheral blood gene expression and imaging biomarkers enhance prediction of radiographic progression in knee osteoarthritis

OBJECTIVE: Predictive biomarkers of progression in knee osteoarthritis are sought to enable clinical trials of structure-modifying drugs. A peripheral blood leukocyte (PBL) inflammatory gene signature, MRI-based bone marrow lesions (BML) and meniscus extrusion scores, meniscal lesions, and osteophyt...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Attur, Mukundan, Krasnokutsky, Svetlana, Zhou, Hua, Samuels, Jonathan, Chang, Gregory, Bencardino, Jenny, Rosenthal, Pamela, Rybak, Leon, Huebner, Janet L., Kraus, Virginia B., Abramson, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488029/
https://ncbi.nlm.nih.gov/pubmed/32912331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02298-6
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