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The combination of an inflammatory peripheral blood gene expression and imaging biomarkers enhance prediction of radiographic progression in knee osteoarthritis

OBJECTIVE: Predictive biomarkers of progression in knee osteoarthritis are sought to enable clinical trials of structure-modifying drugs. A peripheral blood leukocyte (PBL) inflammatory gene signature, MRI-based bone marrow lesions (BML) and meniscus extrusion scores, meniscal lesions, and osteophyt...

詳細記述

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書誌詳細
出版年:Arthritis Res Ther
主要な著者: Attur, Mukundan, Krasnokutsky, Svetlana, Zhou, Hua, Samuels, Jonathan, Chang, Gregory, Bencardino, Jenny, Rosenthal, Pamela, Rybak, Leon, Huebner, Janet L., Kraus, Virginia B., Abramson, Steven B.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488029/
https://ncbi.nlm.nih.gov/pubmed/32912331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02298-6
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