Differential regulation of rho GTPases during lung adenocarcinoma migration and invasion reveals a novel role of the tumor suppressor StarD13 in invadopodia regulation

BACKGROUND: Lung cancer is the second most commonly occurring cancer. The ability to metastasize and spread to distant locations renders the tumor more aggressive. Members of the Rho subfamily of small GTP-binding proteins (GTPases) play a central role in the regulation of the actin cytoskeleton and...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Al Haddad, Maria, El-Rif, Rayane, Hanna, Samer, Jaafar, Leila, Dennaoui, Rayanne, Abdellatef, Sandra, Miskolci, Veronika, Cox, Dianne, Hodgson, Louis, El-Sibai, Mirvat
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487901/
https://ncbi.nlm.nih.gov/pubmed/32900380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00635-5
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