Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells

Palmitoleic acid (POA, 16:1n-7) is a lipokine that has potential nutraceutical use to treat non-alcoholic fatty liver disease. We tested the effects of POA supplementation (daily oral gavage, 300 mg/Kg, 15 days) on murine liver inflammation induced by a high fat diet (HFD, 59% fat, 12 weeks). In HFD...

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Vydáno v:Biochim Biophys Acta Mol Cell Biol Lipids
Hlavní autoři: Souza, Camila O., Teixeira, Alexandre A.S., Biondo, Luana Amorim, Silveira, Loreana Sanches, de Souza Breda, Cristiane N., Braga, Tarcio T., Camara, Niels O.S., Belchior, Thiago, Festuccia, William T., Diniz, Tiego A., Ferreira, Glaucio Monteiro, Hirata, Mario Hiroyuki, Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., Miyamoto, Sayuri, Calder, Philip C., Sethi, Jaswinder K., Rosa Neto, José C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487782/
https://ncbi.nlm.nih.gov/pubmed/32738301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2020.158776
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