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Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer

Targeted drugs disrupting proteins that are dysregulated in cancer have emerged as promising treatments because of their specificity to cancer cell aberrations and thus their improved side effect profile. However, their success remains limited, largely due to existing or emergent therapy resistance....

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Bibliografiske detaljer
Udgivet i:Curr Opin Syst Biol
Main Authors: G.T. Zañudo, Jorge, Steinway, Steven N., Albert, Réka
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487767/
https://ncbi.nlm.nih.gov/pubmed/32954058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2018.02.002
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