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A LINE-1 insertion situated in the promoter of IMPG2 is associated with autosomal recessive progressive retinal atrophy in Lhasa Apso dogs

BACKGROUND: Canine progressive retinal atrophies are a group of hereditary retinal degenerations in dogs characterised by depletion of photoreceptor cells in the retina, which ultimately leads to blindness. PRA in the Lhasa Apso (LA) dog has not previously been clinically characterised or described...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Genet
Κύριοι συγγραφείς: Hitti-Malin, Rebekkah J., Burmeister, Louise M., Ricketts, Sally L., Lewis, Thomas W., Pettitt, Louise, Boursnell, Mike, Schofield, Ellen C., Sargan, David, Mellersh, Cathryn S.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487703/
https://ncbi.nlm.nih.gov/pubmed/32894063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-00911-w
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