Ventilation defects on hyperpolarized helium-3 MRI in asthma are predictive of 2-year exacerbation frequency

BACKGROUND: There is an unmet need for an objective biomarker to predict asthma exacerbations. OBJECTIVE: Here, we assess the ventilation defect percent (VDP) on hyperpolarized (HP) (3)He MRI as a predictor of exacerbation frequency following imaging. METHODS: Subjects underwent HP (3)He MRI and con...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Mummy, David G., Carey, Katherine J., Evans, Michael D., Denlinger, Loren C., Schiebler, Mark L., Sorkness, Ronald L., Jarjour, Nizar N., Fain, Sean B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487001/
https://ncbi.nlm.nih.gov/pubmed/32173351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.02.029
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