Concerted localization-resets precede YAP-dependent transcription

Yes-associated protein 1 (YAP) is a transcriptional regulator with critical roles in mechanotransduction, organ size control, and regeneration. Here, using advanced tools for real-time visualization of native YAP and target gene transcription dynamics, we show that a cycle of fast exodus of nuclear...

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Udgivet i:Nat Commun
Main Authors: Franklin, J. Matthew, Ghosh, Rajarshi P., Shi, Quanming, Reddick, Michael P., Liphardt, Jan T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486942/
https://ncbi.nlm.nih.gov/pubmed/32917893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18368-x
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