Modeling Nanocarrier Transport Across a 3D In Vitro Human Blood-Brain-Barrier Microvasculature

Polymer nanoparticles (NPs), due to their small size and surface functionalization potential has demonstrated effective drug transport across the blood-brain-barrier (BBB). Currently, the lack of in vitro BBB models that closely recapitulate the complex human brain microenvironment contributes to th...

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Veröffentlicht in:Adv Healthc Mater
Hauptverfasser: Ling Lee, Sharon Wei, Campisi, Marco, Osaki, Tatsuya, Possenti, Luca, Mattu, Clara, Adriani, Giulia, Kamm, Roger Dale, Chiono, Valeria
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486802/
https://ncbi.nlm.nih.gov/pubmed/32125776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201901486
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