KSHV LANA acetylation-selective acidic domain reader sequence mediates virus persistence

Viruses modulate biochemical cellular pathways to permit infection. A recently described mechanism mediates selective protein interactions between acidic domain readers and unacetylated, lysine-rich regions, opposite of bromodomain function. Kaposi´s sarcoma (KS)-associated herpesvirus (KSHV) is tig...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Juillard, Franceline, de Miranda, Marta Pires, Li, Shijun, Franco, Aura, Seixas, André F., Liu, Bing, Álvarez, Ángel L., Tan, Min, Szymula, Agnieszka, Kaye, Kenneth M., Simas, J. Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486799/
https://ncbi.nlm.nih.gov/pubmed/32820070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004809117
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