Altered splenic [(89)Zr]Zr-rituximab uptake in patients with interstitial lung disease not responding to rituximab: could this indicate a splenic immune-mediated mechanism?

Rituximab (RTX) for immune-mediated inflammatory disease (IMID) with interstitial pneumonitis (IP) results in non-response in about a third of patients for reasons not well understood. Complete peripheral B-cell depletion in IMID-IP does not seem to correlate with successful treatment outcome. A hyp...

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Veröffentlicht in:Am J Nucl Med Mol Imaging
Hauptverfasser: Adams, Human, Meek, Bob, van de Garde, Ewoudt MW, van Moorsel, Coline HM, Vugts, Danielle J, Keijsers, Ruth G, Grutters, Jan C
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486548/
https://ncbi.nlm.nih.gov/pubmed/32929395
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