Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

Arterial macrophages have different developmental origins, but the association of macrophage ontogeny with their phenotypes and functions in adulthood is still unclear. Here, we combine macrophage fate-mapping analysis with single-cell RNA sequencing to establish their cellular identity during homeo...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Weinberger, Tobias, Esfandyari, Dena, Messerer, Denise, Percin, Gulce, Schleifer, Christian, Thaler, Raffael, Liu, Lulu, Stremmel, Christopher, Schneider, Vanessa, Vagnozzi, Ronald J., Schwanenkamp, Jennifer, Fischer, Maximilian, Busch, Katrin, Klapproth, Kay, Ishikawa-Ankerhold, Hellen, Klösges, Lukas, Titova, Anna, Molkentin, Jeffery D., Kobayashi, Yasuhiro, Engelhardt, Stefan, Massberg, Steffen, Waskow, Claudia, Perdiguero, Elisa Gomez, Schulz, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486394/
https://ncbi.nlm.nih.gov/pubmed/32917889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18287-x
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