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Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes

Immunomolecular characterization of Ehrlichia chaffeensis (E. ch.) and E. canis (E. ca.) has defined protein orthologs, including tandem repeat proteins (TRPs) that have immunodominant linear antibody epitopes. In this study, we combined bioinformatic analysis and cell-free protein expression to ide...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Luo, Tian, Patel, Jignesh G., Zhang, Xiaofeng, Walker, David H., McBride, Jere W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486380/
https://ncbi.nlm.nih.gov/pubmed/32963815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00231-1
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