Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System

Clostridioides difficile infection of the colon leads to severe inflammation and damage to the gastrointestinal epithelium due to the production of potent toxins. This inflammatory tissue damage causes the liberation of high concentrations of host heme at infection sites. Here, we identify the C. di...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Knippel, Reece J., Wexler, Aaron G., Miller, Jeanette M., Beavers, William N., Weiss, Andy, de Crécy-Lagard, Valérie, Edmonds, Katherine A., Giedroc, David P., Skaar, Eric P.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486240/
https://ncbi.nlm.nih.gov/pubmed/32526159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.05.015
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