Mutation-Specific Guide RNA for Compound Heterozygous Porphyria On-target Scarless Correction by CRISPR/Cas9 in Stem Cells

CRISPR/Cas9 is a promising technology for gene correction. However, the edition is often biallelic, and uncontrolled small insertions and deletions (indels) concomitant to precise correction are created. Mutation-specific guide RNAs were recently tested to correct dominant inherited diseases, sparin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Prat, Florence, Toutain, Jérôme, Boutin, Julian, Amintas, Samuel, Cullot, Grégoire, Lalanne, Magalie, Lamrissi-Garcia, Isabelle, Moranvillier, Isabelle, Richard, Emmanuel, Blouin, Jean-Marc, Dabernat, Sandrine, Moreau-Gaudry, François, Bedel, Aurélie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486222/
https://ncbi.nlm.nih.gov/pubmed/32795423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.07.015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados