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Tailoring of the axon initial segment shapes the conversion of synaptic inputs into spiking output in OFF-α T retinal ganglion cells

Recently, mouse OFF-α transient (OFF-α T) retinal ganglion cells (RGCs) were shown to display a gradient of light responses as a function of position along the dorsal-ventral axis; response differences were correlated to differences in the level of excitatory presynaptic input. Here, we show that po...

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Bibliographic Details
Published in:Sci Adv
Main Authors: Werginz, Paul, Raghuram, Vineeth, Fried, Shelley I.
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486099/
https://ncbi.nlm.nih.gov/pubmed/32917708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb6642
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