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CRISPR-mediated Transfection of Brugia malayi

The application of reverse genetics in the human filarial parasites has lagged due to the difficult biology of these organisms. Recently, we developed a co-culture system that permitted the infective larval stage of Brugia malayi to be transfected and efficiently develop to fecund adults. This was e...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Liu, Canhui, Grote, Alexandra, Ghedin, Elodie, Unnasch, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485969/
https://ncbi.nlm.nih.gov/pubmed/32866158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008627
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