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Population and Noncompartmental Pharmacokinetics of Sodium Oxybate Support Weight‐Based Dosing in Children and Adolescents With Narcolepsy With Cataplexy

The pharmacokinetics (PKs) of sodium oxybate (SXB) was evaluated in a subset of participants from a study of SXB treatment in children (aged 7–11 years; n = 11) and adolescents (aged 12–17 years; n = 18) with narcolepsy with cataplexy. PK evaluation was conducted over 2 nights during the period when...

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Dettagli Bibliografici
Pubblicato in:Clin Transl Sci
Autori principali: Chen, Cuiping, Rosen, Carol L., Ruoff, Chad, Boyce, Leslie H., Parvataneni, Rupa, Zomorodi, Katie, Brantley, Scott, Sale, Mark, Plazzi, Giuseppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485950/
https://ncbi.nlm.nih.gov/pubmed/32216084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12780
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