Flavonoids from Rosa roxburghii Tratt prevent reactive oxygen species-mediated DNA damage in thymus cells both combined with and without PARP-1 expression after exposure to radiation in vivo

This study aimed to evaluate the role of FRT in ROS/DNA regulation with or without PARP-1 in radiation-injured thymus cells. The administration of FRT to PARP-1-/- (KO) mice demonstrated that FRT significantly increased the viability of thymus cells and decreased their rate of apoptosis through PARP...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xu, Sai-Juan, Wang, Xia, Wang, Tao-Yang, Lin, Zheng-Zhan, Hu, Yong-Jian, Huang, Zhong-Lin, Yang, Xian-Jun, Xu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485694/
https://ncbi.nlm.nih.gov/pubmed/32862153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103688
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