Calcium Binding Protein Ncs1 Is Calcineurin Regulated in Cryptococcus neoformans and Essential for Cell Division and Virulence

Intracellular calcium (Ca(2+)) is crucial for signal transduction in Cryptococcus neoformans, the major cause of fatal fungal meningitis. The calcineurin pathway is the only Ca(2+)-requiring signaling cascade implicated in cryptococcal stress adaptation and virulence, with Ca(2+) binding mediated by...

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Udgivet i:mSphere
Main Authors: Squizani, Eamim Daidrê, Reuwsaat, Júlia Catarina Vieira, Lev, Sophie, Motta, Heryk, Sperotto, Julia, Kaufman-Francis, Keren, Desmarini, Desmarini, Vainstein, Marilene Henning, Staats, Charley Christian, Djordjevic, Julianne T., Kmetzsch, Lívia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485688/
https://ncbi.nlm.nih.gov/pubmed/32907953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00761-20
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