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Targeting of interleukin-10 receptor by a potential human interleukin-10 peptide efficiently blocks interleukin-10 pathway-dependent cell proliferation

OBJECTIVE: Human interleukin-10 (IL-10) is a dimeric and pleiotropic cytokine that plays a crucial role in cellular immunoregulatory responses. As IL-10 binds to its receptors, IL-10Ra and IL-10Rb, it will suppress or induce the downstream cellular immune responses to protect from diseases. MATERIAL...

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Vydáno v:Tzu Chi Med J
Hlavní autoři: Chang, Chun-Chun, Liu, Cheng-Der, Pan, Sheng-Feng, Huang, Wei-Han, Peng, Chih-Wen, Hsu, Hao-Jen
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer - Medknow 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485672/
https://ncbi.nlm.nih.gov/pubmed/32955521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/tcmj.tcmj_237_19
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